Dr. Shapiro obtained his undergraduate and medical education at McGill University, where he received his M.D.; C.M. degree in 1973. Subsequent to that he completed a residency in internal medicine at the Royal Victoria Hospital in Montreal and at UCLA, spent one year engaged in research in the Department of Epidemiology and Health at McGill, and completed a fellowship at UCLA as a Robert Wood Johnson Clinical Scholar. Dr. Shapiro received a Master of Public Health degree in Health Services from UCLA, then a Ph.D. in history also from UCLA, doing a dissertation on health care services in Portuguese Africa. Dr. Shapiro joined the UCLA faculty in the Division of General Internal Medicine and Health Services Research in 1980; he was promoted to Associate Professor in 1986. In 1988, he established the Primary Care Research Fellowship Program at UCLA, which he directed until 2003. In 1991, he became Chief of the Division of General Internal Medicine and Health Services Research in the Department of Medicine and Associate Director of the UCLA Clinical Scholars Program. He was promoted to Professor of Medicine in 1992 and Professor of Health Services in 2000. From 2002-2003, he served as President of the Society of General Internal Medicine.
Dr. Shapiro's research has focused on the general theme of assuring that medical care is applied equitably and appropriately to the population. In recent years, he has conducted numerous studies in the area of HIV disease. He is an elected member of the American Society of Clinical Investigation and of the Association of American Physicians.